Nexpro HP Combipack


Nexpro HP Combipack is a combination of two antibiotics and an antacid that effectively treats peptic ulcer disease caused due to H. pylori bacterial infection. It fights against the bacteria to treat the infection. It also relieves acidity and discomfort related to the infection.

Nexpro HP Combipack is a prescription medicine. It is advised to take it as per the prescription. It should be taken in an empty stomach, but it must be taken at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The treatment must be completed even if you feel better.

The common side effects of this medicine are nausea, vomiting, diarrhea, rashes, etc. If any of the side effects get aggravated, you must consult your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.

Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Pregnant or breastfeeding women should also consult with their doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy.

Uses of Nexpro HP Kit

  • Peptic ulcer disease

Side effects of Nexpro HP Kit

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nexpro HP

  • Nausea
  • Diarrhea
  • Vomiting
  • Stomach pain
  • Taste change
  • Flatulence
  • Headache
  • Rash

How to use Nexpro HP Kit

Take this medicine in the dose and duration as advised by your doctor. Check the label before use. Nexpro HP Combipack is to be taken empty stomach.

How Nexpro HP Kit works

Nexpro HP Combipack is a combination of three medicines: Amoxycillin, Clarithromycin and Esomeprazole, which treats stomach/intestinal ulcers caused by the bacteria. Amoxycillin is an antibiotic which works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria in the human body. Clarithromycin is also an antibiotic which stops bacterial growth by preventing the synthesis of essential proteins required by the bacteria to carry out vital functions. Together, they eradicate your infection effectively. Esomeprazole is a proton pump inhibitor (PPI) which reduces the amount of acid in the stomach and relieves acid-related indigestion and heartburn.

Safety Advice


Caution is advised when consuming alcohol with Nexpro HP Combipack. Please consult your doctor.


Nexpro HP Combipack may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Nexpro HP Combipack is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.


Nexpro HP Combipack may cause side effects which could affect your ability to drive.
Nexpro HP Combipack can have side effects and the symptoms (such as allergic reactions, dizziness and convulsions) may make you unfit to drive.


Nexpro HP Combipack should be used with caution in patients with kidney disease. Dose adjustment of Nexpro HP Combipack may be needed. Please consult your doctor.


Nexpro HP Combipack is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Nexpro HP Combipack may not be needed in these patients. Please consult your doctor.